Dibenzo-α-pyrones: a new class of larvicidal metabolites against Aedes aegypti from the endophytic fungus Hyalodendriella sp. Ponipodef12.
Identifieur interne : 001444 ( Main/Exploration ); précédent : 001443; suivant : 001445Dibenzo-α-pyrones: a new class of larvicidal metabolites against Aedes aegypti from the endophytic fungus Hyalodendriella sp. Ponipodef12.
Auteurs : Ziling Mao [République populaire de Chine] ; Daowan Lai [République populaire de Chine] ; Xunda Liu [République populaire de Chine] ; Xiaoxiang Fu [République populaire de Chine] ; Jiajia Meng [République populaire de Chine] ; Ali Wang [République populaire de Chine] ; Xiaohan Wang [République populaire de Chine] ; Weibo Sun [République populaire de Chine] ; Zhi Long Liu [République populaire de Chine] ; Ligang Zhou [République populaire de Chine] ; Yang Liu [République populaire de Chine]Source :
- Pest management science [ 1526-4998 ] ; 2017.
Descripteurs français
- KwdFr :
- Aedes (effets des médicaments et des substances chimiques), Animaux (MeSH), Antibactériens (pharmacologie), Ascomycota (composition chimique), Ascomycota (métabolisme), Bacillus subtilis (effets des médicaments et des substances chimiques), Fongicides industriels (pharmacologie), Insecticides (MeSH), Larve (effets des médicaments et des substances chimiques), Magnaporthe (effets des médicaments et des substances chimiques), Produits biologiques (composition chimique), Produits biologiques (pharmacologie), Pyrones (composition chimique), Pyrones (isolement et purification), Pyrones (pharmacologie), Relation structure-activité (MeSH), Xanthomonas vesicatoria (effets des médicaments et des substances chimiques).
- MESH :
- composition chimique : Ascomycota, Produits biologiques, Pyrones.
- effets des médicaments et des substances chimiques : Aedes, Bacillus subtilis, Larve, Magnaporthe, Xanthomonas vesicatoria.
- isolement et purification : Pyrones.
- métabolisme : Ascomycota.
- pharmacologie : Antibactériens, Fongicides industriels, Produits biologiques, Pyrones.
- Animaux, Insecticides, Relation structure-activité.
English descriptors
- KwdEn :
- Aedes (drug effects), Animals (MeSH), Anti-Bacterial Agents (pharmacology), Ascomycota (chemistry), Ascomycota (metabolism), Bacillus subtilis (drug effects), Biological Products (chemistry), Biological Products (pharmacology), Fungicides, Industrial (pharmacology), Insecticides (MeSH), Larva (drug effects), Magnaporthe (drug effects), Pyrones (chemistry), Pyrones (isolation & purification), Pyrones (pharmacology), Structure-Activity Relationship (MeSH), Xanthomonas vesicatoria (drug effects).
- MESH :
- chemical , chemistry : Biological Products, Pyrones.
- chemical , isolation & purification : Pyrones.
- chemical , pharmacology : Anti-Bacterial Agents, Biological Products, Fungicides, Industrial, Pyrones.
- chemistry : Ascomycota.
- drug effects : Aedes, Bacillus subtilis, Larva, Magnaporthe, Xanthomonas vesicatoria.
- metabolism : Ascomycota.
- Animals, Insecticides, Structure-Activity Relationship.
Abstract
BACKGROUND
In our search for new agrochemicals from endophytic fungi, the crude extract of the endophytic Hyalodendriella sp. Ponipodef12 associated with the hybrid 'Neva' of Populus deltoides Marsh × P. nigra L. was found to possess larvicidal activity against Aedes aegypti.
RESULTS
Fractionation of the extract has led to the isolation of 11 dibenzo-α-pyrones (1-11), including three new congeners: hyalodendriols A-C (1-3). The structures of the new compounds were elucidated by comprehensive spectroscopic analyses, including the modified Mosher's method for the assignment of the absolute configuration. Compounds 2-7 showed potent larvicidal activities against the fourth-instar larvae of A. aegypti with IC
CONCLUSION
Our study revealed dibenzo-α-pyrones to be a new class of larvicidal metabolites against A. aegypti. © 2016 Society of Chemical Industry.
DOI: 10.1002/ps.4481
PubMed: 27862895
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Sun</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Zhi Long" sort="Liu, Zhi Long" uniqKey="Liu Z" first="Zhi Long" last="Liu">Zhi Long Liu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Entomology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Entomology, College of Plant 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Ponipodef12.</title><author><name sortKey="Mao, Ziling" sort="Mao, Ziling" uniqKey="Mao Z" first="Ziling" last="Mao">Ziling Mao</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Lai, Daowan" sort="Lai, Daowan" uniqKey="Lai D" first="Daowan" last="Lai">Daowan Lai</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Xunda" sort="Liu, Xunda" uniqKey="Liu X" first="Xunda" last="Liu">Xunda Liu</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Fu, Xiaoxiang" sort="Fu, Xiaoxiang" uniqKey="Fu X" first="Xiaoxiang" last="Fu">Xiaoxiang Fu</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Meng, Jiajia" sort="Meng, Jiajia" uniqKey="Meng J" first="Jiajia" last="Meng">Jiajia Meng</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Ali" sort="Wang, Ali" uniqKey="Wang A" first="Ali" last="Wang">Ali Wang</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Xiaohan" sort="Wang, Xiaohan" uniqKey="Wang X" first="Xiaohan" last="Wang">Xiaohan Wang</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Sun, Weibo" sort="Sun, Weibo" uniqKey="Sun W" first="Weibo" last="Sun">Weibo Sun</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Zhi Long" sort="Liu, Zhi Long" uniqKey="Liu Z" first="Zhi Long" last="Liu">Zhi Long Liu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Entomology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Entomology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Ligang" sort="Zhou, Ligang" uniqKey="Zhou L" first="Ligang" last="Zhou">Ligang Zhou</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Yang" sort="Liu, Yang" uniqKey="Liu Y" first="Yang" last="Liu">Yang Liu</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Processing, Ministry of Agriculture, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Processing, Ministry of Agriculture, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Pest management science</title><idno type="eISSN">1526-4998</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aedes (drug effects)</term><term>Animals (MeSH)</term><term>Anti-Bacterial Agents (pharmacology)</term><term>Ascomycota (chemistry)</term><term>Ascomycota (metabolism)</term><term>Bacillus subtilis (drug effects)</term><term>Biological Products (chemistry)</term><term>Biological Products (pharmacology)</term><term>Fungicides, Industrial (pharmacology)</term><term>Insecticides (MeSH)</term><term>Larva (drug effects)</term><term>Magnaporthe (drug effects)</term><term>Pyrones (chemistry)</term><term>Pyrones (isolation & purification)</term><term>Pyrones (pharmacology)</term><term>Structure-Activity Relationship (MeSH)</term><term>Xanthomonas vesicatoria (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aedes (effets des médicaments et des substances chimiques)</term><term>Animaux (MeSH)</term><term>Antibactériens (pharmacologie)</term><term>Ascomycota (composition chimique)</term><term>Ascomycota (métabolisme)</term><term>Bacillus subtilis (effets des médicaments et des substances chimiques)</term><term>Fongicides industriels (pharmacologie)</term><term>Insecticides (MeSH)</term><term>Larve (effets des médicaments et des substances chimiques)</term><term>Magnaporthe (effets des médicaments et des substances chimiques)</term><term>Produits biologiques (composition chimique)</term><term>Produits biologiques (pharmacologie)</term><term>Pyrones (composition chimique)</term><term>Pyrones (isolement et purification)</term><term>Pyrones (pharmacologie)</term><term>Relation structure-activité (MeSH)</term><term>Xanthomonas vesicatoria (effets des médicaments et des substances chimiques)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Biological Products</term><term>Pyrones</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Pyrones</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Biological Products</term><term>Fungicides, Industrial</term><term>Pyrones</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Ascomycota</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Ascomycota</term><term>Produits biologiques</term><term>Pyrones</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Aedes</term><term>Bacillus subtilis</term><term>Larva</term><term>Magnaporthe</term><term>Xanthomonas vesicatoria</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Aedes</term><term>Bacillus subtilis</term><term>Larve</term><term>Magnaporthe</term><term>Xanthomonas vesicatoria</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Pyrones</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Ascomycota</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Ascomycota</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antibactériens</term><term>Fongicides industriels</term><term>Produits biologiques</term><term>Pyrones</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Insecticides</term><term>Structure-Activity Relationship</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Insecticides</term><term>Relation structure-activité</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>In our search for new agrochemicals from endophytic fungi, the crude extract of the endophytic Hyalodendriella sp. Ponipodef12 associated with the hybrid 'Neva' of Populus deltoides Marsh × P. nigra L. was found to possess larvicidal activity against Aedes aegypti.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Fractionation of the extract has led to the isolation of 11 dibenzo-α-pyrones (1-11), including three new congeners: hyalodendriols A-C (1-3). The structures of the new compounds were elucidated by comprehensive spectroscopic analyses, including the modified Mosher's method for the assignment of the absolute configuration. Compounds 2-7 showed potent larvicidal activities against the fourth-instar larvae of A. aegypti with IC</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Our study revealed dibenzo-α-pyrones to be a new class of larvicidal metabolites against A. aegypti. © 2016 Society of Chemical Industry.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27862895</PMID><DateCompleted><Year>2018</Year><Month>07</Month><Day>06</Day></DateCompleted><DateRevised><Year>2018</Year><Month>07</Month><Day>06</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1526-4998</ISSN><JournalIssue CitedMedium="Internet"><Volume>73</Volume><Issue>7</Issue><PubDate><Year>2017</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Pest management science</Title><ISOAbbreviation>Pest Manag Sci</ISOAbbreviation></Journal><ArticleTitle>Dibenzo-α-pyrones: a new class of larvicidal metabolites against Aedes aegypti from the endophytic fungus Hyalodendriella sp. Ponipodef12.</ArticleTitle><Pagination><MedlinePgn>1478-1485</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/ps.4481</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In our search for new agrochemicals from endophytic fungi, the crude extract of the endophytic Hyalodendriella sp. Ponipodef12 associated with the hybrid 'Neva' of Populus deltoides Marsh × P. nigra L. was found to possess larvicidal activity against Aedes aegypti.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Fractionation of the extract has led to the isolation of 11 dibenzo-α-pyrones (1-11), including three new congeners: hyalodendriols A-C (1-3). The structures of the new compounds were elucidated by comprehensive spectroscopic analyses, including the modified Mosher's method for the assignment of the absolute configuration. Compounds 2-7 showed potent larvicidal activities against the fourth-instar larvae of A. aegypti with IC<sub>50</sub> values ranging from 7.21 to 120.81 µg mL<sup>-1</sup> . Among them, penicilliumolide D (6) displayed the strongest activity (IC<sub>50</sub> = 7.21 µg mL<sup>-1</sup> ). A structure-larvicidal activity relationship was discussed. The possible mode of action of these compounds was assessed for their acetylcholinesterase inhibitory activities. In addition, hyalodendriol C (3) displayed antibacterial activity against Bacillus subtilis and Xanthomonas vesicatoria, and exhibited strong inhibition against the spore germination of Magnaporthe oryzae.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Our study revealed dibenzo-α-pyrones to be a new class of larvicidal metabolites against A. aegypti. © 2016 Society of Chemical Industry.</AbstractText><CopyrightInformation>© 2016 Society of Chemical Industry.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mao</LastName><ForeName>Ziling</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lai</LastName><ForeName>Daowan</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Xunda</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fu</LastName><ForeName>Xiaoxiang</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meng</LastName><ForeName>Jiajia</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Ali</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Xiaohan</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Weibo</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Zhi Long</ForeName><Initials>ZL</Initials><AffiliationInfo><Affiliation>Department of Entomology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Ligang</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Yang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-products Processing, Ministry of Agriculture, Beijing, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>01</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Pest Manag Sci</MedlineTA><NlmUniqueID>100898744</NlmUniqueID><ISSNLinking>1526-498X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001688">Biological Products</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005659">Fungicides, Industrial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007306">Insecticides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011753">Pyrones</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000330" MajorTopicYN="N">Aedes</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001203" MajorTopicYN="N">Ascomycota</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001412" MajorTopicYN="N">Bacillus subtilis</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001688" MajorTopicYN="N">Biological Products</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005659" MajorTopicYN="N">Fungicides, Industrial</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007306" MajorTopicYN="Y">Insecticides</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007814" MajorTopicYN="N">Larva</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020082" MajorTopicYN="N">Magnaporthe</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011753" MajorTopicYN="N">Pyrones</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013329" MajorTopicYN="N">Structure-Activity Relationship</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D044184" MajorTopicYN="N">Xanthomonas vesicatoria</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Aedes aegypti</Keyword><Keyword MajorTopicYN="N">Hyalodendriella</Keyword><Keyword MajorTopicYN="N">antibacterial</Keyword><Keyword MajorTopicYN="N">antifungal</Keyword><Keyword MajorTopicYN="N">dibenzo-α-pyrone</Keyword><Keyword MajorTopicYN="N">larvicidal activity</Keyword><Keyword MajorTopicYN="N">mosquito</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>08</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>10</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>11</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>7</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>11</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27862895</ArticleId><ArticleId IdType="doi">10.1002/ps.4481</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Mao, Ziling" sort="Mao, Ziling" uniqKey="Mao Z" first="Ziling" last="Mao">Ziling Mao</name></noRegion><name sortKey="Fu, Xiaoxiang" sort="Fu, Xiaoxiang" uniqKey="Fu X" first="Xiaoxiang" last="Fu">Xiaoxiang Fu</name><name sortKey="Lai, Daowan" sort="Lai, Daowan" uniqKey="Lai D" first="Daowan" last="Lai">Daowan Lai</name><name sortKey="Liu, Xunda" sort="Liu, Xunda" uniqKey="Liu X" first="Xunda" last="Liu">Xunda Liu</name><name sortKey="Liu, Yang" sort="Liu, Yang" uniqKey="Liu Y" first="Yang" last="Liu">Yang Liu</name><name sortKey="Liu, Zhi Long" sort="Liu, Zhi Long" uniqKey="Liu Z" first="Zhi Long" last="Liu">Zhi Long Liu</name><name sortKey="Meng, Jiajia" sort="Meng, Jiajia" uniqKey="Meng J" first="Jiajia" last="Meng">Jiajia Meng</name><name sortKey="Sun, Weibo" sort="Sun, Weibo" uniqKey="Sun W" first="Weibo" last="Sun">Weibo Sun</name><name sortKey="Wang, Ali" sort="Wang, Ali" uniqKey="Wang A" first="Ali" last="Wang">Ali Wang</name><name sortKey="Wang, Xiaohan" sort="Wang, Xiaohan" uniqKey="Wang X" first="Xiaohan" last="Wang">Xiaohan Wang</name><name sortKey="Zhou, Ligang" sort="Zhou, Ligang" uniqKey="Zhou L" first="Ligang" last="Zhou">Ligang Zhou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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